Meditaliano IMAT Prep

Lesson 6: Cell Structure I - The Fundamentals

Introduction: The Basic Unit of Life

Welcome to Lesson 6. The cell is the fundamental structural and functional unit of all known organisms. In this lesson, we will explore the two primary types of cells—prokaryotic and eukaryotic—and then take a detailed tour of the sophisticated internal structures, or organelles, that allow eukaryotic cells to perform their complex functions.

Learning Objectives

  • LO 6.1: Compare and contrast the key features of prokaryotic and eukaryotic cells.
  • LO 6.2: Describe the structure and function of the nucleus, endomembrane system (ER, Golgi, lysosomes), mitochondria, and peroxisomes.
  • LO 6.3: Identify the three main components of the cytoskeleton and describe their respective roles in cell shape, motility, and organization.
  • LO 6.4: Distinguish between a typical animal cell and a plant cell, explaining the functions of the cell wall, chloroplasts, and central vacuole.

Part 1: Prokaryotes vs. Eukaryotes

All life can be categorized into two major domains based on cellular structure: Prokaryotes (bacteria and archaea) and Eukaryotes (protists, fungi, plants, and animals). The primary distinction is the presence of a true, membrane-bound nucleus and other organelles in eukaryotes.

Diagram: Prokaryotic vs. Eukaryotic Cell Structure

A comparative diagram showing a simple prokaryotic cell on the left and a more complex, organelle-filled eukaryotic cell on the right. Prokaryotic Cell Cytoplasm Nucleoid (DNA) Ribosomes Plasma Membrane Eukaryotic Cell (Animal) Cytoplasm Nucleus Mitochondrion ER Ribosomes
FeatureProkaryotesEukaryotes
NucleusAbsent. Genetic material is in a nucleoid region.Present. A double membrane encloses the DNA.
Membrane-Bound OrganellesAbsent (no mitochondria, ER, Golgi, etc.).Present. Allows for compartmentalization of functions.
DNA StructureSingle, circular chromosome.Multiple, linear chromosomes complexed with proteins (chromatin).
SizeTypically small (1-5 μm).Typically larger (10-100 μm).
RibosomesSmaller (70S).Larger (80S in cytoplasm; 70S in mitochondria/chloroplasts).
Cell WallUsually present, made of peptidoglycan (in bacteria).Present in plants (cellulose) and fungi (chitin); absent in animals.

Part 2: The Eukaryotic Cell: A Detailed Tour

2.1 The Nucleus & Ribosomes: Information and Synthesis

The nucleus contains the cell's genetic material (DNA) and controls cell activities by regulating gene expression. The nuclear envelope is a double membrane with nuclear pores that regulate transport. The nucleolus is where ribosomal RNA (rRNA) is synthesized. Ribosomes, made of rRNA and protein, translate genetic information into proteins, either free in the cytosol or bound to the ER.

2.2 The Endomembrane System: Manufacturing and Shipping

This is a network of interconnected internal membranes that work together to synthesize, modify, package, and transport lipids and proteins.

Diagram: The Endomembrane System Workflow

A diagram showing the flow of protein synthesis and transport from the nucleus and rough ER, through the Golgi apparatus, and into a transport vesicle for secretion. Nucleus Rough ER Golgi Apparatuscistrans Secretion

2.3 Mitochondria & Peroxisomes: Energy and Metabolism

The mitochondrion is the site of cellular respiration. It has a double membrane; the inner membrane is folded into cristae. The inner compartment is the mitochondrial matrix. Peroxisomes are metabolic compartments that use oxygen to break down fatty acids and detoxify harmful substances, producing and then neutralizing hydrogen peroxide.

Diagram: Structure of Mitochondrion and Peroxisome

A cross-section diagram of a mitochondrion and a peroxisome. Mitochondrion Outer Membrane Inner Membrane Cristae Matrix Peroxisome Enzymes (e.g., Catalase)

2.4 The Cytoskeleton: Support and Motility

The cytoskeleton is a network of protein fibers that organizes the cell’s structures and activities. It is composed of three main types of fibers:

Diagram: Components of the Cytoskeleton

Microtubule Hollow tube of tubulin Microfilament Intertwined strands of actin Intermediate Filament Fibrous proteins coiled into cables

Part 3: Plant Cells vs. Animal Cells

Plant cells have several unique structures not found in animal cells, which are related to their different lifestyles.

StructureFunctionFound In
Cell WallMaintains cell shape, protects the cell, prevents excessive water uptake. Made of cellulose.Plants, Fungi, Prokaryotes (not animals)
ChloroplastsSite of photosynthesis, converting solar energy to chemical energy.Plants and some protists
Central VacuoleStores water, ions, and nutrients; maintains turgor pressure; breaks down waste.Mature plant cells
LysosomesDigestion and recycling of macromolecules.Animal cells (rare in plants)
CentrosomesRegion where microtubules are initiated; contains centrioles in animal cells.Animal cells

Diagram: Unique Structures of a Plant Cell

Cell Wall Plasma Membrane Chloroplast Central Vacuole

Interactive Practice Quiz

Test your understanding of cell structure. Choose the best answer for each question (A-E) and then submit to see your results.