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2026/27 Complete Master Guide

San Raffaele Milan

Vita-Salute San Raffaele University (UniSR) • International MD Program

Train inside IRCCS Ospedale San Raffaele—Europe premier hospital for gene therapy, robotic surgery, and advanced medical research. Featuring an English-taught 6-year MD degree, high-yield clinical exposure, and strong international residency pathways.

Gene Therapy & Research Pioneer

IRCCS Ospedale San Raffaele

Milan, Italy · 1,350+ Beds · World-Class IRCCS

Annual Capacity

64 Non-EU / 86 EU

Exam Blueprint

60 Qs (60% Logic / 40% Science)

Cutoff Benchmark

38.75 / 60 Points

Annual Tuition

€20,000 / year (4 parts)

Campus gallery

See where you will study

University Campus Panorama - University Campus Panorama
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University Campus Panorama - Medical Lecture Theatre
University Campus Panorama - Biotechnology Workshop
University Campus Panorama - Biomedical Research Team
1/6 · University Campus Panorama

Degree

Medicine & Surgery (MD)

Hospital

IRCCS San Raffaele

Exam

60 Qs (60% Logic Weight)

Duration

6 Years (360 ECTS)

Deposit

€1,500 (3-5 day window)

Campus

Milan, Italy

Academic & Scientific Leadership

World-Renowned Biomedical Research & Clinical Excellence

Vita-Salute San Raffaele University is intimately integrated with IRCCS Ospedale San Raffaele, an internationally acclaimed biomedical research hospital and scientific institute.

Global pioneer in translational medicine, cellular therapy, and gene therapy (San Raffaele Telethon Institute for Gene Therapy - SR-TIGET).

Over 1,350 beds and 50+ specialized clinical departments, handling complex multi-organ surgeries and rare disease referrals.

Active clinical trial portfolio with direct student involvement in cutting-edge molecular oncology, cardiovascular research, and neurosciences.

High faculty-to-student ratio ensuring intensive bedside mentoring throughout 6 years of medical studies.

Key Hospital Metrics & Infrastructure

1,350+ Beds

Hospital Capacity

One of largest research hospitals in Europe

40+ Theaters

Operating Suites

Robotic, hybrid vascular & neurosurgery

1,000,000+

Annual Patients

Broad clinical diversity & rare diseases

Top Tier

Scientific Impact

Pioneered world first approved gene therapies

Examination Blueprint

60 Questions in 60 Minutes

The San Raffaele test is distinctive for placing 60% of total score weight on Logic, Problem Solving, and Critical Reading, giving candidates with strong analytical skills a massive competitive edge.

+1.0

Correct

-0.25

Incorrect

0

Blank

7 Reserve Calibration Questions

The exam includes 7 additional unscored questions used by the testing committee for psychometric calibration. Candidates answer all 67 questions within the allotted time.

Section Breakdown & Weighting

Logic, Problem Solving & Reading Comprehension (36 Questions)60% Weight

Critical reasoning, textual comprehension, analytical problem solving, data sufficiency, numerical patterns, and logical syllogisms. This section carries 60% of total score weight.

Scientific Knowledge: Biology, Chemistry, Math & Physics (24 Questions)40% Weight

Core natural sciences: Biology (cellular biology, genetics, physiology), Chemistry (organic, stoichiometry, solutions), Mathematics (algebra, functions, geometry), and Physics (mechanics, thermodynamics, electricity).

Total Scored Points:60.0 Points
Historical Non-EU Cutoff:~38.75 / 60 Points
Tie-Breaking Hierarchy:Logic Score > Science Score > Younger Age
360 ECTS Comprehensive Structure

Full 6-Year Medical Degree Syllabus

Accredited under European Union Directive 2005/36/EC. Preclinical foundations and intensive clinical rotations in IRCCS San Raffaele hospital wards.

YEAR 01

Year 1: Foundations of Medicine, Molecules & Morphological Sciences

Cellular Systems, Biochemistry, Gross Anatomy & Medical Biophysics

60 ECTS / CFU
6 ECTS

Medical Physics, Biophysics & Computer Science

Radiation physics, bioelectricity, optical diagnostics, fluid mechanics, biomedical data analysis.

10 ECTS

Chemistry & Foundations of Medical Biochemistry

Chemical equilibria, thermodynamics, enzyme kinetics, metabolic bioenergetics, structural lipidomics, and proteomics.

9 ECTS

Cellular & Molecular Biology

Membrane transport mechanisms, organellar trafficking, signaling cascades, epigenetic control, apoptosis.

8 ECTS

Histology, Cytology & Human Embryology

Microscopic tissue architecture, stem cell biology, early embryonic germ layer specialization, organogenesis.

10 ECTS

Human Gross Anatomy I (Locomotor & Thoracic)

Musculoskeletal biomechanics, cardiovascular morphology, mediastinal anatomy, respiratory system, clinical radiological correlates.

7 ECTS

Medical Humanities, Bioethics & Philosophy of Science

Doctor-patient communication, deontological ethics, clinical empathy, history of medical thought, and patient autonomy.

10 ECTS

Basic Life Support (BLS-D) & Patient Care Simulation

Cardiopulmonary resuscitation, defibrillation, first aid skills, simulation lab training at IRCCS San Raffaele.

Clinical Clerkship Focus: Clinical Skills Simulation Lab & Basic Nursing Immersion at IRCCS San Raffaele.

YEAR 02

Year 2: Neuroanatomy, Human Physiology & Mechanisms of Disease

Integrative Physiology, Immunology, Microbiology & Genetics

60 ECTS / CFU
10 ECTS

Human Gross Anatomy II (Neuroanatomy & Viscera)

Cranial nerves, central and peripheral neural pathways, digestive, urogenital, and endocrine structural morphology.

15 ECTS

Human Physiology I & II

Cardiac electrophysiology, pulmonary mechanics, renal clearance and acid-base regulation, digestive secretomotor activity, endocrine axes.

10 ECTS

General Pathology & Pathophysiology

Cellular injury and adaptation, acute/chronic inflammation, tissue repair, hemodynamic disorders, thrombosis, molecular oncology.

7 ECTS

Immunology & Immunopathology

Innate and adaptive immunity, lymphocyte activation, hypersensitivity, autoimmune pathologies, primary/secondary immunodeficiencies.

8 ECTS

Medical Microbiology & Virology

Bacterial virulence factors, antimicrobial resistance, viral replication strategies, mycoses, and clinical parasitology.

5 ECTS

Medical Genetics & Genomic Medicine

Mendelian and complex inheritance, genomic sequencing analysis, oncogenomics, targeted genetic therapies, and clinical counseling.

5 ECTS

Introductory Physical Semeiotics Workshop

Hands-on physical examination techniques, vital signs, chest auscultation, abdominal palpation, and medical history taking.

Clinical Clerkship Focus: Physical Semeiotics & Basic Nursing Clerkship in San Raffaele Inpatient Units.

YEAR 03

Year 3: Pathology, Pharmacology & Core Clinical Rotations

Systemic Pathology, Clinical Pharmacology & Inpatient Wards

60 ECTS / CFU
12 ECTS

Systemic Anatomic Pathology

Histopathological diagnosis of cardiovascular, pulmonary, gastrointestinal, hepatic, renal, endocrine, and skin diseases; biopsy interpretation.

10 ECTS

General & Clinical Pharmacology

Pharmacodynamics, pharmacokinetics, autonomic pharmacology, cardiovascular agents, chemotherapy, toxicology, personalized medicine.

10 ECTS

Medical & Surgical Semeiotics (Methodology)

Clinical diagnostic reasoning, differential diagnosis formulation, symptom analysis, and bedside presentation.

6 ECTS

Laboratory Medicine & Molecular Diagnostics

Clinical hematology, biochemical biomarkers, coagulation profiling, urinalysis, and point-of-care testing technologies.

6 ECTS

Cardiovascular System Diseases

Coronary artery disease, heart failure, arrhythmias, valvular disorders, hypertension, interventional catheterization.

6 ECTS

Respiratory System Diseases

COPD, asthma, interstitial lung diseases, pulmonary embolism, pneumonia, thoracic oncology, and non-invasive ventilation.

10 ECTS

Inpatient Bedside Clinical Clerkships

Daily ward rounds in Internal Medicine and General Surgery, patient case management, and morning clinical meetings.

Clinical Clerkship Focus: Daily Bedside Clinical Clerkships at IRCCS Ospedale San Raffaele (Medicine & Surgery Wards).

YEAR 04

Year 4: Specialized Medical & Surgical Disciplines

Organ-System Subspecialties & Multidisciplinary Oncology

60 ECTS / CFU
7 ECTS

Gastroenterology, Hepatology & Endoscopy

GI bleeding, inflammatory bowel disease, viral hepatitis, cirrhosis, pancreatitis, diagnostic and interventional endoscopy.

7 ECTS

Endocrinology, Diabetology & Metabolism

Thyroid pathology, pituitary disorders, adrenal insufficiency, diabetes management, metabolic bone diseases.

7 ECTS

Nephrology, Dialysis & Urology

Acute and chronic renal failure, glomerulonephritis, hemodialysis and transplantation, urological cancers, and lithiasis.

5 ECTS

Rheumatology & Autoimmune Disorders

Rheumatoid arthritis, SLE, systemic sclerosis, spondyloarthropathies, vasculitides, and biological targeted therapies.

6 ECTS

Hematology & Transfusion Medicine

Leukemias, lymphomas, myeloma, hemolytic anemias, bone marrow transplantation, and hemotherapy protocols.

6 ECTS

Medical Oncology & Cancer Immunotherapy

Oncogenesis, molecular tumor profiling, immune checkpoint inhibitors, chemotherapy regimens, palliative care.

8 ECTS

Diagnostic Imaging & Interventional Radiology

X-ray, ultrasound, CT, MRI, PET-CT protocols, interventional vascular and oncological radiological procedures.

14 ECTS

Subspecialty Outpatient & Inpatient Rotations

Rotations across specialized clinical units, endoscopy suites, and multidisciplinary tumor boards.

Clinical Clerkship Focus: Subspecialty Outpatient Clinics, Endoscopy Suites & Multidisciplinary Tumor Boards at San Raffaele.

YEAR 05

Year 5: Neuroscience, Sensory Organs & Maternal-Child Health

Clinical Neurosciences, Head & Neck, Musculoskeletal & Pediatrics

60 ECTS / CFU
8 ECTS

Neurology & Clinical Neurophysiology

Stroke units, epilepsy, neurodegenerative diseases, multiple sclerosis, peripheral neuropathies, neurocritical care.

4 ECTS

Neurosurgery & Minimally Invasive Approaches

Intracranial neoplasms, aneurysms, neurotrauma, spine surgery, robotic and endoscopic neurosurgery.

6 ECTS

Psychiatry & Behavioral Health

Depressive and bipolar disorders, schizophrenia, anxiety disorders, psychopharmacology, emergency psychiatry.

6 ECTS

Orthopedics, Traumatology & Sports Medicine

Fracture management, joint reconstruction (hip, knee), spine surgery, arthroscopy, and musculoskeletal rehabilitation.

4 ECTS

Ophthalmology & Visual Sciences

Refractive surgery, cataract, glaucoma, retinal diseases, ocular emergencies, and neuro-ophthalmology.

4 ECTS

Otorhinolaryngology & Head-Neck Surgery

ENT oncology, otology, audiology, rhinology, airway management, and reconstructive head and neck surgery.

5 ECTS

Dermatology, Venereology & Plastic Surgery

Inflammatory skin disorders, melanoma, cutaneous surgery, aesthetic and reconstructive plastic surgery.

8 ECTS

Obstetrics, Gynecology & Reproductive Medicine

High-risk pregnancy, labor management, gynecological oncology, minimally invasive laparoscopic surgery, IVF.

8 ECTS

Pediatrics, Neonatology & Pediatric Specialties

Neonatal intensive care, growth disorders, pediatric infections, pediatric emergency triage, congenital diseases.

7 ECTS

Surgical Theater & Maternity Traineeships

Scrubbed-in surgical training, labor ward assistance, and pediatric emergency clerkships.

Clinical Clerkship Focus: Operating Room Surgical Clerkships, Labor & Delivery Wards, and Pediatric Emergency Department.

YEAR 06

Year 6: Critical Care, Evaluative Traineeship (TPV) & MD Thesis

Emergency Medicine, Official Licensing Internship & Degree Defense

60 ECTS / CFU
6 ECTS

Emergency Medicine & Acute Trauma Care

Shock management, mass casualty triage, ACLS protocols, trauma resuscitation, emergency point-of-care ultrasound (POCUS).

6 ECTS

Intensive Care, Anesthesiology & Pain Medicine

Invasive monitoring, ventilator management, perioperative care, regional/general anesthesia, palliative analgesia.

3 ECTS

Clinical Toxicology & Poisoning Emergencies

Acute drug intoxications, biological toxins, industrial poisonings, antidotal treatments, and dialysis detoxification.

4 ECTS

Forensic Medicine, Deontology & Healthcare Law

Medical liability, ethics in intensive care, patient consent, autopsy findings, and professional jurisprudence.

4 ECTS

Public Health, Hygiene & Global Health Systems

Hospital infection control, epidemiology, health economics, preventative medicine, and global health policy.

5 ECTS

Practical Evaluative Traineeship (TPV Internal Medicine)

Official licensing clinical rotation in Internal Medicine inpatient units.

5 ECTS

Practical Evaluative Traineeship (TPV General Surgery)

Official licensing clinical rotation in General Surgery operating and ward units.

5 ECTS

Practical Evaluative Traineeship (TPV General Practice)

Official licensing clinical rotation with accredited primary care physicians.

22 ECTS

Experimental Research MD Thesis Defense

Independent scientific thesis based on laboratory or clinical investigation defended before the university degree commission.

Clinical Clerkship Focus: Full-Time Practical Sub-Internships in Emergency Department, Intensive Care Units & Primary Care.

Transparent Financial Schedule

Tuition Fees & Confirmation Deposit

Tuition for the International MD Program is €20,000 per academic year, payable in 4 structured installments.

Advance Seat Confirmation Deposit

€1,500

📅 Within 3-5 working days of merit ranking

Mandatory non-refundable deposit to officially reserve your seat allocation.

First Tuition Installment

€8,500

📅 October / Academic Enrollment

Covers formal registration, clinical simulation center fees, library database access.

Second Tuition Installment

€5,000

📅 January / Semester 1 Mid-Term

Covers semester 1 exam sessions and laboratory credentials.

Third Tuition Installment

€5,000

📅 April / Semester 2 Commencement

Covers hospital clinical clerkships, liability insurance, and summer rotations.

Strategic Pathway

8-Step Application & Visa Roadmap

Step-by-step roadmap from exam registration to arriving on campus in Milan.

01

Verify 12-Year Secondary Education

Confirm you hold or will complete a high school diploma earned after at least 12 years of formal education with strong scientific coursework.

02

Register on the UniSR Online Portal

Create your personal credentials on the official UniSR portal (unisr.it), upload your passport, and select the International MD Program.

03

Pay Test Registration Fee (€200)

Complete online payment of the €200 test registration fee before the booking deadline to confirm your examination slot.

04

Sit the San Raffaele Admission Test

Complete the 60-question computer-based exam in 60 minutes (+7 reserve questions). Available at global test centers and via certified online proctoring.

05

Merit Ranking & Advance Deposit (€1,500)

Rankings are released within 7-10 days. Admitted candidates must confirm their place and pay the €1,500 deposit within 3-5 working days.

06

Submit Universitaly Pre-Enrollment (Non-EU)

Non-EU students submit their visa pre-enrollment application on Universitaly, selecting Vita-Salute San Raffaele University.

07

Obtain Document Legalization (CIMEA or DOV)

Secure the CIMEA Statement of Comparability & Verification or the consular Declaration of Value for your secondary school diploma.

08

Receive Student Visa & Matriculate in Milan

Obtain your Italian Type D National Student Visa, arrive in Milan, apply for your residency permit (Permesso di Soggiorno), and begin classes.

Frequently Asked Questions

Key questions on San Raffaele admissions, testing, and hospital life.

How are the questions distributed on the San Raffaele Test?

The exam consists of 60 scored questions in 60 minutes, heavily weighted toward Logic and Problem Solving (36 questions / 60%) alongside Natural Sciences (24 questions / 40%: Biology, Chemistry, Math, and Physics). In addition, 7 unscored reserve questions are included for test calibration.

What was the historical admission cutoff for Non-EU and EU applicants?

The historical first-round cutoff for Non-EU applicants typically sits around 38.75 to 42.0 out of 60 points. EU cutoffs generally range slightly higher (43.0 to 47.0 points). Through waitlist scrolling (scorrimenti), final cutoffs often drop by several points.

What makes IRCCS San Raffaele a pioneer in medical research?

IRCCS Ospedale San Raffaele is internationally celebrated for groundbreaking biomedical research, having pioneered the world first stem-cell gene therapies (Strimvelis). With over 1,350 beds and 50+ specialized clinical departments, students learn directly from world-leading clinical researchers.

What is the tuition fee structure at San Raffaele?

Tuition for the International MD Program is a flat €20,000 per academic year, payable in an advance deposit of €1,500 followed by three installments (€8,500 + €5,000 + €5,000).

Are Italian language classes provided for international students?

Yes. All coursework is in English, but students are required to achieve B1/B2 Italian proficiency before starting clinical hospital rotations in Year 3. UniSR provides comprehensive, credit-bearing Italian language courses throughout Years 1 and 2.

Can San Raffaele graduates enter US or UK residency programs?

Yes. The MD degree is fully accredited across the EU (Directive 2005/36/EC), listed in WDOMS, and recognized by the US ECFMG / USMLE and UK General Medical Council (GMC). Many UniSR alumni secure residency matches in the US, UK, Switzerland, and Germany.

Does San Raffaele provide student accommodation on campus?

Yes. The Cascina Melghera student residence is located directly on the university campus, providing private single rooms, study lounges, laundry facilities, and dining options within steps of the hospital.

How does waitlist scrolling (scorrimento) work at San Raffaele?

Because top-scoring students frequently receive simultaneous offers from Cattolica, Humanitas, and public IMAT universities, seats that are not confirmed within the 3-5 day window are immediately offered to subsequent candidates on the merit list in successive weekly rounds.

Ready to Prepare for San Raffaele Milan?

Get targeted coaching for the 60% Logic weight of the UniSR test, simulation exams, and complete application guidance with Meditaliano.